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Ann Thorac Surg. 2015 Jan;99(1):e3-5

第一作者兼通讯作者：Raffa GM

Mediterranean Institute for Transplantation and Advanced Specialized Therapies (ISMETT), Palermo, Italy. Electronic address: [email protected].

既往关于地中海贫血患者接受瓣膜手术预后的报告极少，据作者所知，文献中报告的此类病例仅有7例。地中海贫血患者经常会遇到心脏瓣膜疾病，而进行瓣膜置换时存在较高的人工瓣膜并发症风险，包括血栓形成和肺栓塞（即使进行了优化抗凝治疗）。该研究报告了1例地中海贫血患者发生真菌性瓣膜心内膜炎后成功进行主动脉瓣修复病例的长期预后。

Abstract

Outcome after heart valve surgery in patients affected by thalassemia is an unreported issue and to the best of our knowledge only 7 cases have been described in the literature. Heart valve disease is commonly encountered in thalassemia patients and heart valve replacement carries high risk of prosthesis complications including thrombosis and embolization despite optimal anticoagulation management. We report a successful long-term outcome after a case of aortic valve repair after mycotic valve endocarditis.

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